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Nobel Prize 2023. From Failure to Salvation: The Development of mRNA Vaccines Against COVID-19
The recipients of the 2022 Novo Nordisk Prize and the 2023 Nobel Prize in Physiology and Medicine tell the story behind the development: the failures, the persistence and the distrust in the technology they are now certain will also revolutionise the approach to treating many otherwise severe diseases. When the world was locked down because of the COVID-19 pandemic, a miracle was needed to reopen it. Vaccine researchers around the world dropped what they were doing to join the collective race against the new virus. The first to reach the finish line was considered a real outsider: the mRNA vaccine. However, many people do not know that the work on mRNA as a new drug class started decades ago.
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The brain – more than just a control centre for chemical signals?
Billions and billions of tiny neurons have joined together over millions of years to form what we now call the human brain. Unsurprisingly, this organ harbours some of the most thoroughly explored and yet least known areas of the body. The research includes how the brain sends and receives signals to and from the rest of the body to how tiny chemical changes in the brain can lead to neurodegenerative disorders such as Parkinson’s disease or mental disorders such as schizophrenia.
