Dan Stærk Follow Dan
Professor
Peptides and Proteins, Department of Drug Design and Pharmacology, University of Copenhagen
Biography
Professor Dan Staerk is heading the Natural Products Research group and Copenhagen Small-Molecule NMR Center. His research interests include discovery of small-molecule and peptide-based drug leads from natural sources like medicinal plants, marine organisms, and microorganisms, with disease areas covering type 2 diabetes, infectious diseases (antibacterial and antifungal compounds), and cancer. Another line of research includes sustainable drug discovery as well as development of sustainable functional food from sources like food by-products and biosynthetically modified organisms. A central part of his research is development and application of new state-of-the-art bioanalytical techniques for advanced chemical and pharmacological profiling of complex extracts. This includes high-resolution bioactivity profiling and ligand fishing for identification of bioactive constituents in crude extracts - followed by HPLC-PDA-HRMS-SPE-NMR analysis for full structural identification.