Jonas Thue Treebak
Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen
The research activities of my group are directed towards interrogating the signaling pathways controlling cellular and whole body glucose and lipid homeostasis in cell-based and animal models. To resolve the physiological role of genes, proteins, and pathways that regulate insulin action and adiposity, we use transgenic animals harboring mutant and wild-type forms of candidate genes or knockout deletions. We are developing in vitro and in vivo methods to assess the functional role of novel targets in type 2 diabetes and obesity pathogenesis as well as performing clinical and experimental studies for genotype/phenotype interactions to identify diabetes risk and mechanisms underlying diabetes pathogenesis.