Department of Molecular Biology and Genetics, Aarhus University
Our research group studies dynamic and disordered proteins using biophysical and biochemical methods. We are especially interested in intrinsically disordered proteins, that are completely devoid of a fixed three-dimensional structure.
Intrinsically disordered proteins challenge the dominant paradigm in molecular biology – that the structure of a molecule defines its function. Instead, the function is defined by a higher diverse ensemble of conformation. We aim to understand how.
We use synthetic biology to design new intrinsically disordered proteins with two goals in mind: We seek to understand the design principles of intrinsically disordered proteins and to develop new proteins that can be used in biotechnology.