Dennis Vestergaard Pedersen
Department of Molecular Biology and Genetics, Aarhus University
The research conducted in the section for protein science explores the relationship between the three dimensional structure of the studied macromolecules (proteins and nucleic acids) and their function. For determination of atomic models, we primarily use cryo-electron microscopy and x-ray crystallography supplemented with small angle X-ray scattering. Mass spectrometry is extensively used to for identification of proteins and functional/structural characterization of proteins. Mass spectrometry is also used for biomarker analysis in models of human disease including metabolic, neurodegenerative and inflammatory diseases.