Anders H. Lund
Professor and Group Leader
Biotech Research & Innovation Centre (BRIC), University of Copenhagen
The aim of the laboratory is to unveil fundamental biological mechanisms and understand how these become perturbed during diseases, most prominently cancer, with the ambition that our findings may contribute to the development of clinical tools.
With the realization that 80% of the genome is transcribed and only 2% serve as coding regions, the non-coding part of the transcriptome is likely to hold key to understanding many essential biological phenomena as well as pathologies. To explore this, we focus on the functions of long non-coding RNA in cancer with a special focus on cellular senescence.
Technically, the lab spans widely and includes the identification of disease-relevant genes in functional screens, advanced next-gen sequencing techniques, genetic and biochemical studies in cell culture models and advanced mouse genetics.