Division of Coating Technology, KTH Royal Institute of Technology, Stockholm
My research group works with both state of the art computer simulations and experimental protein engineering to understand life at the atomistic level. Enzymes are natural biocatalysts that are essential for the living cell. This is perhaps well illustrated by the fact that fundamental and organizational tasks, for instance energy generation and information processing, would take millions - or even billion - of years in the absence of biocatalysts, which represent timescales that would be incompatible with life.
Enzyme catalysis evolved in an aqueous environment and water constitutes a cornerstone for the chemistry of life. Our research aims for an enhanced understanding of the impact of solvent dynamics on enzyme catalysis and motion which is currently poorly understood and usually neglected.Towards reaching this goal we bridge fundamental chemical principles with biotechnology.