Till Bartke Følg Till
Deputy Director
Institute of Functional Epigenetics, Helmholtz Munich, Germany
Biografi
Our mission is to understand: How are genes packaged within the nucleus of a cell? How does DNA organization regulate gene expression? How does the marking of genomic regions with distinct small chemical modifications establish a cellular memory? We utilize cutting-edge technologies to observe, predict, and manipulate how these processes respond to environmental and developmental signals in individual cells.
The human body is composed of more than 200 different cell types. Each of our body’s cells contains the same hereditary information encoded in around 30,000 genes. Each gene serves as a plan for a protein that can be produced during a process called gene expression. However, our cells do not express all genes, only the ones required for their function. Thus, different cell types express different sets of genes. But how do our cells control which genes are active?