My laboratory applies systems biology approaches to investigate microbe-microbe and host-microbe interactions with the aim of improving our ability to exploit and manipulate microbial communities in relation to management and use of biological resources as well as infectious disease control.
Specific research areas include:
* Investigations of bacterial pathogens in relation to chronic infections in humans
* Identification of the molecular mechanisms that underlie microbial adaptation, evolution and survival in dynamic, antibiotic-rich environments.
* Exploring the feedback between microbial interactions and evolution within complex microbial communities.
My laboratory develops and applies a range of bacterial genetics and genomics based methods – including high-throughput genome sequencing - as well as systems biology data analysis tools.