Jacob Giehm Mikkelsen
Professor
Department of Biomedicine, Aarhus University, Denmark.
Biografi
Jacob Giehm Mikkelsen is Professor MSO at the Department of Biomedicine, Aarhus University. His research centres on advancing genome engineering and gene-therapy technologies, with a particular focus on viral and non-viral gene delivery, CRISPR-based gene editing, and the molecular mechanisms that underlie disease.
At the Giehm Lab, his team develops and applies genome-wide screening tools to investigate cancer drug resistance, gene regulation in cancer and innate immunity, and gene correction strategies for primary immunodeficiencies. Their work utilises state-of-the-art pathogen vectors, transposons and gene-editing platforms to explore new therapeutic concepts.
Mikkelsen has published extensively in the fields of viral vectors, hematopoietic stem cell engineering, CRISPR/Cas9 gene editing and molecular medicine. His work aims not only at understanding disease mechanisms but also at translating this understanding into novel gene-therapeutic strategies.
